Natural Human Urokinase protein (ab51966)

製品の概要

製品の詳細

  • 由来
    Native
  • 由来
    Native
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab51966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Source: Human urine Ab51966 is a two-chain glycoprotein containing 411 amino acids with 12 dissulfide bonds. Its molecular weight is 54 kDa.
  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab51966 purity was assessed also by HPLC. Endotoxin: Less than 0.1 ng/mg of human Urokinase
  • 製品の状態
    Lyophilised
  • 備考
    Source: Human urine Ab51966 is a two-chain glycoprotein containing 411 amino acids with 12 dissulfide bonds. Its molecular weight is 54 kDa.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • 再構成
    Reconstitute in sterile water to a concentration >100 µg/ml. Add a carrier protein (0.1% HSA or BSA) for extrastability.

関連情報

  • 別名
    • ATF
    • ATF uPA
    • BDPLT5
    • Plasminogen activator
    • Plasminogen activator urinary
    • Plasminogen activator urokinase
    • PLAU
    • QPD
    • u PA
    • U plasminogen activator
    • u-PA
    • U-plasminogen activator
    • uPA
    • URK
    • UROK_HUMAN
    • Urokinase plasminogen activator
    • Urokinase type plasminogen activator
    • Urokinase type plasminogen activator precursor
    • Urokinase-type plasminogen activator chain B
    see all
  • 機能
    Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • 組織特異性
    Expressed in the prostate gland and prostate cancers.
  • 配列類似性
    Belongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • 翻訳後修飾
    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab51966 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for your enquiry. This product was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer and hence is Tris free.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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