Natural Human TIMP2 protein (ab39314)

製品の概要

製品の詳細

  • 由来Natural
  • 由来Native
  • アミノ酸配列 1
    • 生物種Human
    アミノ酸配列 2
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab39314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

  • 精製度> 95 % SDS-PAGE.
    TIMP2 is purified from human fibroblasts, and is essentially free of contaminating MMPs or other known TIMPs.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, PBS, pH 7.4

関連情報

  • 別名
    • CSC 21K
    • CSC-21K
    • CSC21K
    • Metalloproteinase inhibitor 2
    • Metalloproteinase inhibitor 2 precursor
    • TIMP 2
    • TIMP metallopeptidase inhibitor 2
    • TIMP-2
    • TIMP2
    • TIMP2_HUMAN
    • Tissue Inhibitor of Metalloproteinase 2
    • Tissue inhibitor of metalloproteinases 2
    see all
  • 機能Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
  • 配列類似性Belongs to the protease inhibitor I35 (TIMP) family.
    Contains 1 NTR domain.
  • 翻訳後修飾The activity of TIMP2 is dependent on the presence of disulfide bonds.
  • 細胞内局在Secreted.
  • Information by UniProt

Natural Human TIMP2 protein (ab39314) 使用論文

ab39314 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.
The molecular weight of ab39314 is 24,398g/mol and the extinction co-efficient is 33160cm-1M-1. Unfortunately I do not have any information on its use for titration of mmp14
If there is anything else I can help...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"