Natural Human Serum Albumin protein (FITC) (ab8030)

製品の概要

法規制情報

製品の詳細

  • 由来
    Native
  • 由来
    Native
  • 標識
    FITC. Ex: 493nm, Em: 528nm

特性

Our Abpromise guarantee covers the use of ab8030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Flow Cytometry

    Immunomicroscopy

  • 製品の状態
    Lyophilised
  • 備考

    Fluorochrome/Protein Ratio: 1.5 moles FITC per mole of Human Albumin

     

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.

    Preservative: 0.01% Sodium Azide
    Constituents: 10mg/ml Polyethylene Glycol, 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2

  • 再構成
    Reconstitue with 1.0 mL of deionized water

関連情報

  • 別名
    • alb
    • ALBU_HUMAN
    • Albumin
    • Albumin (32 AA)
    • Albumin (AA 34)
    • Analbuminemia
    • Bisalbuminemia
    • Cell growth inhibiting protein 42
    • DKFZp779N1935
    • Dysalbuminemic hyperthyroxinemia
    • Growth inhibiting protein 20
    • HSA
    • Hyperthyroxinemia dysalbuminemic
    • PRO0883
    • PRO0903
    • PRO1341
    • Serum albumin
    see all
  • 機能
    Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
  • 組織特異性
    Plasma.
  • 関連疾患
    Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
  • 配列類似性
    Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • 翻訳後修飾
    Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

This product has been referenced in:
  • Zadravec P  et al. Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit. PLoS One 11:e0162625 (2016). ELISA . Read more (PubMed: 27606705) »

See 1 Publication for this product

レビューと Q&A

Our product number AB8030, Human Serum Albumin (FITC), contains only 10mg/ml Polyethylene Glycol, 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2 as a storage buffer.

I have heard back from the lab about whether the FITC tag alters the structure of the protein. They have told me that we do not have specific data on how the FITC tag affects the protein structure, but they have seen data experiments using a monoclonal...

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I am still waiting to hear from the lab about any possible structural alterations to HSA when FITC tagged. In regards to the quote that you requested, we are in the process of generating that quote but I just need to confirm you address and contact ph...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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