製品の概要

  • 製品名
    Natural Human IgM Kappa protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Native
  • 由来
    Native
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      49 kDa
    • 領域
      1 to 452

特性

Our Abpromise guarantee covers the use of ab99015 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • 備考
    Starting material tested and found negative for HIV I & II antibodies, Hepatits B surface antigen and Hepatitis C antibodies.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: 0.2M Sodium chloride, 50mM Tris, pH 8.0

関連情報

  • 別名
    • Ig mu chain C region
    • IGHM
  • 関連性
    IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences. Immunoglobulin (Ig) molecules consist of two chains, one heavy chain (which can be alpha, delta, epsilon, gamma or mu) and one light chain (which can be kappa or lambda) each consisting of a variable and a constant region. An IgM molecule contains thus a mu heavy chain combined with either a kappa or a lambda light chains. It is found almost exclusively as an homopentamer in the serum. Membrane-bound IgM molecules are non-covalently associated with heterodimer of CD79A and CD79B.
  • 細胞内局在
    Isoform 1: Secreted. Isoform 2: Cell membrane; Single-pass type I membrane protein.

参考文献

ab99015 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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