Natural Human Haptoglobin protein (ab77872)

製品の概要

製品の詳細

  • 由来Natural
  • 由来Native
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab77872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Sandwich ELISA

  • 精製度> 95 % SDS-PAGE.
    >95% pure (SDS-PAGE): polymorphic form (mixture of 1-1, 2-1, and/or 2-2)
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Deionized water.

  • 再構成Reconstitute using deionized water.

関連情報

  • 別名
    • Binding peptide
    • BP
    • Haptoglobin alpha chain
    • Haptoglobin alpha(1S) beta
    • Haptoglobin alpha(2FS) beta
    • Haptoglobin beta chain
    • Haptoglobin, alpha polypeptide
    • Haptoglobin, beta polypeptide
    • HP
    • HP2 ALPHA2
    • HP2ALPHA2
    • HPA1S
    • HPT
    • HPT_HUMAN
    • MGC111141
    • Zonulin
    see all
  • 機能As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
    Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
  • 組織特異性Expressed by the liver and secreted in plasma.
  • 関連疾患Anhaptoglobinemia
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
    Contains 2 Sushi (CCP/SCR) domains.
  • 細胞内局在Secreted.
  • Information by UniProt

Natural Human Haptoglobin protein 画像

Natural Human Haptoglobin protein (ab77872) 使用論文

ab77872 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.

I just checked our current stock of these proteins and they should both arrive lyophilized. For ab90924, the concentration indicated on the printed datasheet (4.76 mg/mL) will reflect the volume from which the protei...

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Thank you for contacting us.

These proteins are provided in lyophilized form and as such, the concentrations will be reconstitution dependent. I hope this helps, please let me know if you need any additional information or assistance.

Thank you for your recent telephone enquiry.
I can confirm the following information regarding our haptoglobin proteins:

ab77872 Haptoglobin protein
This protein is purified from a mix of donors and so contains all 3 forms.
<...

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Thank you for your explanation and clarification.

I can confirm and reassure you that ab77872: Haptoglobin protein does not contain any buffer components. The haptoglobinwas in water before lyophilization.

I hope this information wi...

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Thank you for your enquiry and your interest in our products.

You are absolutely correct. I can confirm that this product is sold in lyophilised form; it needs to be reconstituted in deionized water.

If you need any further assistan...

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I understand the difficulty that you are having, finding a standard for your experiments. Though the previous lot was a suitable standard, I think the product in general is not, since it is not validated for consistency among lots with regards to sugar...

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I am sorry to deliver the report I received from our supplier: "Catalog ab77872 Purified Human Haptoglobin is not tested in our laboratory for the distribution of sugar groups. (The two lots in question) are 2 different purification events using th...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"