Natural human Gamma Thrombin protein (ab81592)

製品の概要

  • 製品名Natural human Gamma Thrombin protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Natural
  • 由来Native
  • アミノ酸配列
    • 生物種Human
    • 領域328 to 622

特性

Our Abpromise guarantee covers the use of ab81592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性<1% Thrombin activity. Specific activity is determined by Fibrinogen clotting assay relative to NIH standard thrombin. 1 NIH Unit = 1.15 IS Units
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 6.50
    Constituents: 0.1% Polyethylene glycol, 1.64% Sodium phosphate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Activation peptide fragment 1
    • Activation peptide fragment 2
    • Cf 2
    • Cf2
    • Coagulation factor II
    • Coagulation factor II (thrombin)
    • FII
    • Prepro coagulation factor II
    • Prothrombin
    • Prothrombin B chain
    • PT
    • RP23-176N9.4
    • RPRGL2
    • Serine protease
    • THPH1
    • Thrombin heavy chain
    • Thrombin light chain
    see all
  • 関連性Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. Gamma Thrombin is a proteolyzed form of Alpha Thrombin. Gamma Thrombin consists of four chains (A, B1, B5, B4) with a disulfide link between the A peptide and the B5 peptide.
  • 細胞内局在Secreted, extracellular space.

Natural human Gamma Thrombin protein (ab81592) 使用論文

ab81592 has not yet been referenced specifically in any publications.

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