Native Human Collagen V protein (ab7537)
Key features and details
- Expression system: Native
- Suitable for: SDS-PAGE, WB, IP, ELISA
製品の詳細
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製品名
Native Human Collagen V protein
Collagen V タンパク質・ペプチド 製品一覧 -
生理活性
Collagen taken from human species. -
発現系
Native -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Native -
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生物種
Human -
予測される分子量
184 kDa
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab7537 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Western blot
Immunoprecipitation
ELISA
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製品の状態
Liquid -
備考
This product is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type V. Reaction with anti-Collagen I, II, III, IV or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).
Collagen taken from human species.
Denaturing and reducing conditions will greatly diminish reactivity and selectivity of this protein.
Purity: Human Collagen Type V has been prepared from Human Placenta and is chromatographically and immunologically pure.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide
Constituent: 0.06% Acetic acid
関連情報
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別名
- AB collagen
- Alpha 1 type V collagen
- Alpha 2 type V collagen
see all -
機能
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. -
関連疾患
Ehlers-Danlos syndrome 1
Ehlers-Danlos syndrome 2 -
配列類似性
Belongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 laminin G-like domain. -
ドメイン
The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function. -
翻訳後修飾
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Sulfated on 40% of tyrosines. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab7537 は論文での使用が確認できていません。