Native Human Apolipoprotein CII/ApoC-II (ab90925)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
製品の詳細
-
製品名
Native Human Apolipoprotein CII/ApoC-II
Apolipoprotein CII/ApoC-II タンパク質・ペプチド 製品一覧 -
精製度
> 95 % SDS-PAGE. -
発現系
Native -
タンパク質長
Full length protein -
Animal free
No -
由来
Native -
-
生物種
Human
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab90925 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
-
製品の状態
Lyophilized -
備考
Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.This product was previously labelled as Apolipoprotein CII
-
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Store at -20ºC.
pH: 7.40
Constituent: 0.079% Ammonium bicarbonate -
再構成After initial centrifugation, we suggest the addition of the lyophilization buffer (10 mM ammonium bicarbonate, pH 7.4) to the original volume, followed by gentle swirling and/or vortexing to ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.
関連情報
-
別名
- APC 2
- APC2
- Apo CII
see all -
機能
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. -
組織特異性
Liver and intestine. -
関連疾患
Hyperlipoproteinemia 1B -
配列類似性
Belongs to the apolipoprotein C2 family. -
翻訳後修飾
Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing.
Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma. -
細胞内局在
Secreted. - Information by UniProt
画像
-
SDS-PAGE analysis of ab90925 on an 18% Tris-Glycine Gel
Lane 1: Apolipoprotein CII/ApoC-II - 10 μg (Reduced/heated)
Lane 2: Apolipoprotein CII/ApoC-II - 15 μg (Reduced/heated)
Lane 3: Molecular weight markers
Lane 4: Apolipoprotein CII/ApoC-II - 10 μg (Non-reduced/no heat)
Lane 5: Apolipoprotein CII/ApoC-II - 20 μg (Non-reduced/no heat)
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab90925 は論文での使用が確認できていません。