製品の概要

製品の詳細

  • 由来Natural
  • 由来Native
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab77903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab77903 is purified by Column chromatography. There is a single arc by IEP against whole human serum.
  • 製品の状態Lyophilised
  • 備考All human source materials have tested negative for HIV 1, HIV 2, anti-HCV, anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 50mM Sodium carbonate, 10mM Sodium deoxycholate, pH 10.0

  • 再構成Reconstitute with 147ul distilled water.

関連情報

  • 別名
    • Apo B-100
    • Apo B-48
    • APOB
    • ApoB 100
    • ApoB 48
    • APOB_HUMAN
    • Apolipoprotein B
    • Apolipoprotein B 100
    • Apolipoprotein B-48
    • Apolipoprotein B48
    • FLDB
    • LDLCQ4
    see all
  • 機能Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • 関連疾患Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • 配列類似性Contains 1 vitellogenin domain.
  • 翻訳後修飾Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • 細胞内局在Cytoplasm. Secreted.
  • Information by UniProt

Natural Human Apolipoprotein B (ab77903) 使用論文

This product has been referenced in:
  • Disterer P  et al. Exon Skipping of Hepatic APOB Pre-mRNA With Splice-switching Oligonucleotides Reduces LDL Cholesterol In Vivo. Mol Ther 21:602-9 (2013). WB . Read more (PubMed: 23319054) »

See 1 Publication for this product

Product Wall

Thank you for your enquiry and your interest in our products. I can confirm that all these 3 products (ab77859, ab77903, ab82277) do not have Apo B-48. I hope this information will be useful for you.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"