Natural B. pertussis Pertussis toxin protein (ab63830)

製品の概要

  • 製品名Natural B. pertussis Pertussis toxin protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Natural
  • 由来Native
  • アミノ酸配列
    • 生物種Bordetella pertussis
    • 配列の追加情報Pertussis toxin protein consists of one molecule of each subunit 1 (26 kDa), subunit 2 (22 kDa), subunit 3 (22 kDa), subunit 5 (12 kDa) and two molecules of subunit 4 (12 kDa).

特性

Our Abpromise guarantee covers the use of ab63830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 製品の状態Liquid
  • 備考


    ab63830 can be used for: 1. Studies on signal transduction by the trimeric GTP-binding proteins. 2. Therapeutic role in treating a number of diseases including hypertension, viral inhibition, and autoimumune inhibition.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.0268% PBS, 10% Glycerol, 0.8% Sodium chloride

関連情報

  • 別名
    • IAP S1
    • IAP S2
    • IAP S3
    • IAP S4
    • IAP S5
    • Islet activating protein S1
    • Islet activating protein S2
    • Islet activating protein S3
    • Islet activating protein S4
    • Islet activating protein S5
    • NAD dependent ADP ribosyltransferase
    • Pertussis toxin subunit 1
    • Pertussis toxin subunit 2
    • Pertussis toxin subunit 3
    • Pertussis toxin subunit 4
    • Pertussis toxin subunit 5
    • PTX S1
    • PTX S2
    • PTX S3
    • PTX S4
    • PTX S5
    • PtxA
    • PtxB
    • PtxC
    • PtxD
    • PtxE
    see all
  • 関連性Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by Bordetella pertussis. PT catalyzes the ADP-ribosylation of the alpha subunits of the heterotrimeric guanine nucleotide regulatory proteins Gi, Go, and Gt and prevents intracellular signal transduction by preventing the G proteins from interacting with G protein-coupled receptors on the cell membrane. PT consists of one molecule each of S1 (26 kDa), S2 (22 kDa), S3 (22 kDa), S5 (12 kDa) and two molecules of S4 (12 kDa).
  • 細胞内局在Secreted

Natural B. pertussis Pertussis toxin protein 画像

  • ab63830 on SDS-PAGE.
  • Left Panel: Control CHO cell culture without Pertussis Toxin. Right Panel: CHO cells treated with Pertussis Toxin at 0.1 ng/ml in the culture medium for 17 hr at 37oC.

Natural B. pertussis Pertussis toxin protein (ab63830) 使用論文

ab63830 has not yet been referenced specifically in any publications.

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Thank you for contacting us.

The protein can be shipped at 4C. However upon arrival it sould be stored at -80C.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information...

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Thank you for your patient. I can confirm the toxin was produced from phase 1 Bordetella pertussis Tohama strain. I hope this information is helpful. Please do not hesitate to contact us if you need further advice or information.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"