製品の概要

  • 製品名
    Anti-Natriuretic peptides A antibody
    Natriuretic peptides A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Natriuretic peptides A
  • アプリケーション
    適用あり: ICC, ICC/IF, RIAmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Guinea pig, Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide corresponding to Rat Natriuretic peptides A aa 124-151.
    Sequence:

    SLRRSSCFGGRIDRIGAQSGLGCNSFRY


    Database link: P01161

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution. PubMed: 20544856
RIA 1/3000.

ターゲット情報

  • 機能
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 関連疾患
    Atrial standstill 2
    Atrial fibrillation, familial, 6
  • 配列類似性
    Belongs to the natriuretic peptide family.
  • 翻訳後修飾
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANF antibody
    • ANF_HUMAN antibody
    • ANP antibody
    • ATFB6 antibody
    • Atrial natriuretic factor antibody
    • Atrial natriuretic peptide antibody
    • Atriopeptin antibody
    • Cardiodilatin antibody
    • Cardiodilatin related peptide antibody
    • Cardiodilatin-related peptide antibody
    • Cardionatrin antibody
    • CDD ANF antibody
    • CDD antibody
    • CDD-ANF antibody
    • CDP antibody
    • Natriuretic peptide A antibody
    • Natriuretic peptide precursor A antibody
    • NPPA antibody
    • PND antibody
    • Prepronatriodilatin antibody
    see all

参考文献

This product has been referenced in:
  • Zheng C  et al. Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy. Front Pharmacol 8:222 (2017). WB ; Mouse . Read more (PubMed: 28487655) »
  • Christoforou N  et al. Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. PLoS One 8:e63577 (2013). ICC/IF . Read more (PubMed: 23704920) »

See all 4 Publications for this product

レビューと Q&A

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry
Sample
Rat Cell (astrocytes)
Specification
astrocytes
Fixative
Paraformaldehyde
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10%
Username

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Verified customer

投稿 Jan 05 2006

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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