Anti-Natriuretic Peptide Receptor A 抗体 (ab40817)


  • 製品名Anti-Natriuretic Peptide Receptor A antibody
    Natriuretic Peptide Receptor A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Natriuretic Peptide Receptor A
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 750 - 850 of Human Natriuretic Peptide Receptor A.

    (Peptide available as ab41439.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Kidney (Human) Tissue Lysate - adult normal tissue



Our Abpromise guarantee covers the use of ab40817 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 119 kDa).
ICC/IF Use a concentration of 1 µg/ml.


  • 機能Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
  • 配列類似性Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 1 guanylate cyclase domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Phosphorylation of the protein kinase-like domain is required for full activation by ANP.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANP-A antibody
    • ANPa antibody
    • ANPR-A antibody
    • ANPRA antibody
    • ANPRA_HUMAN antibody
    • Atrial natriuretic peptide A type receptor antibody
    • Atrial natriuretic peptide receptor 1 antibody
    • Atrial natriuretic peptide receptor A antibody
    • Atrial natriuretic peptide receptor type A antibody
    • Atrionatriuretic peptide receptor A antibody
    • GC A antibody
    • GC-A antibody
    • Guanylate cyclase A antibody
    • Guanylate cyclase antibody
    • GUC2A antibody
    • GUCY2A antibody
    • Natriuretic peptide A type receptor antibody
    • Natriuretic peptide receptor A/guanylate cyclase A antibody
    • NPR-A antibody
    • NPR1 antibody
    • NPRA antibody
    see all

Anti-Natriuretic Peptide Receptor A antibody 画像

  • Anti-Natriuretic Peptide Receptor A antibody (ab40817) at 1 µg/ml + Human kidney tissue lysate - total protein (ab30203) at 10 µg

    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 119 kDa
    Observed band size : 140 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.
  • ICC/IF image of ab40817 stained human HEK 293 cells. The cells were methanol fixed (5 min), permabilised in TBS-T (20 min) and incubated with the antibody (ab40817, 1µg/ml) for 1h at room temperature. 1%BSA / 10% normal goat serum / 0.3M glycine was used to quench autofluorescence and block non-specific protein-protein interactions. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red). DAPI was used to stain the cell nuclei (blue).

Anti-Natriuretic Peptide Receptor A antibody (ab40817) 使用論文

ab40817 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Rat Tissue sections (Brain sections)
Specification Brain sections
Fixative Paraformaldehyde
Antigen retrieval step None
Permeabilization No

Dr. Sophie Pezet

Verified customer

投稿 Jun 05 2009