製品の概要

  • 製品名Anti-NASP antibody
    NASP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NASP
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide within Human NASP aa 626-675 (internal sequence). The exact sequence is proprietary.
    Sequence:

    KEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLV


    Database link: NP_689511

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab94779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 85 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
  • 組織特異性Isoform 1 is testis- and sperm-specific.
  • 配列類似性Belongs to the NASP family.
    Contains 3 TPR repeats.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
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Anti-NASP antibody 画像

  • Anti-NASP antibody (ab94779) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 85 kDa
    Gel concentration: 12%

    Note: the observed bank corresponds to isoform 2.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling NASP with ab94779 at 5µg/ml.

Anti-NASP antibody (ab94779) 使用論文

ab94779 has not yet been referenced specifically in any publications.

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