Anti-NAS6 抗体 (ab91447)
Key features and details
- Rabbit polyclonal to NAS6
- Suitable for: WB, IP
- Reacts with: Saccharomyces cerevisiae
- Isotype: IgG
製品の概要
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製品名
Anti-NAS6 antibody -
製品の詳細
Rabbit polyclonal to NAS6 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IPmore details -
種交差性
交差種: Saccharomyces cerevisiae -
免疫原
Recombinant full length Saccharomyces cerevisiae NAS6 protein, expressed in E. coli.
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ポジティブ・コントロール
- Crude extract of S. cerevisiae
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 6
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.1% BSA, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab91447の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/5000. Predicted molecular weight: 26 kDa.
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IP |
Use at an assay dependent dilution.
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特記事項 |
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WB
1/5000. Predicted molecular weight: 26 kDa. |
IP
Use at an assay dependent dilution. |
ターゲット情報
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関連性
NAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD. -
細胞内局在
Cytosol; Nucleus; Proteasome complex -
参照データベース
- Entrez Gene: 853147 Saccharomyces cerevisiae
- SwissProt: P50086 Saccharomyces cerevisiae
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別名
- Nas6p antibody
- ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6 antibody
- Probable 26S proteasome regulatory subunit p28 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab91447 は 2 報の論文で使用されています。
- Greene ER et al. Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. Elife 8:N/A (2019). PubMed: 31778111
- Rousseau A & Bertolotti A An evolutionarily conserved pathway controls proteasome homeostasis. Nature 536:184-9 (2016). WB . PubMed: 27462806