製品の概要

  • 製品名Anti-NALP12 antibody
    NALP12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to NALP12
  • 特異性Multiple isoforms of NALP12 are known to exist. ab105409 is predicted to not cross-react with other NALP family members.
  • アプリケーション適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    An 18 amino acid peptide from near the N terminus of Human NALP12 (NP_653288).

  • ポジティブ・コントロール
    • Human brain tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 120 kDa.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
  • 組織特異性Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.
  • 関連疾患Defects in NLRP12 are the cause of familial cold autoinflammatory syndrome type 2 (FCAS2) [MIM:611762]. FCAS are rare autosomal dominant systemic inflammatory diseases characterized by episodes of rash, arthralgia, fever and conjunctivitis after generalized exposure to cold.
  • 配列類似性Belongs to the NLRP family.
    Contains 1 DAPIN domain.
    Contains 8 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CLR19.3 antibody
    • FCAS2 antibody
    • Monarch 1 antibody
    • Monarch-1 antibody
    • NACHT, leucine rich repeat and PYD containing 12 antibody
    • NACHT, LRR and PYD containing protein 12 antibody
    • NACHT, LRR and PYD domains-containing protein 12 antibody
    • NAL12_HUMAN antibody
    • NLR family, pyrin domain containing 12 antibody
    • NLRP12 antibody
    • Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12 antibody
    • OTTHUMP00000067227 antibody
    • PAN6 antibody
    • PYPAF7 antibody
    • PYRIN containing APAF1 like protein 7 antibody
    • PYRIN-containing APAF1-like protein 7 antibody
    • Regulated by nitric oxide antibody
    • RNO antibody
    • RNO2 antibody
    see all

Anti-NALP12 antibody 画像

  • Immunofluorescence of NALP12 in Human brain tissue with ab105409 at 20 ug/mL.

  • Immunohistochemistry of Human brain tissue with ab105409 5 μg/mL.

  • Anti-NALP12 antibody (ab105409) at 1 µg/ml + Human brain tissue lysate at 15 µg

    Predicted band size : 120 kDa

Anti-NALP12 antibody (ab105409) 使用論文

ab105409 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105409.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"