製品の概要

  • 製品名Naftopidil hydrochloride
  • 製品の詳細
    α1 Adrenoceptor antagonist
  • 生理活性の詳細α1 Adrenoceptor antagonist. pKi values are 3.7, 20 and 1.2 for α1a, α1b and α1d, respectively. Orally active. Implicated in benign prostate hyperplasia and bladder obstruction. Antihypertensive.
  • 精製度> 98%

製品の特性

    Naftopidil hydrochloride (ab120756) 使用論文

    This product has been referenced in:
    • Kanda H  et al. Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int J Cancer 122:444-51 (2008). Read more (PubMed: 17918159) »
    • Takei R  et al. Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol 79:447-54 (1999). Read more (PubMed: 10361884) »
    • Yamada S  et al. Binding characteristics of naftopidil and alpha 1-adrenoceptor antagonists to prostatic alpha-adrenoceptors in benign prostatic hypertrophy. Life Sci 50:127-35 (1992). Read more (PubMed: 1370569) »

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