製品の概要

  • 製品名Anti-Nac1 antibody
    Nac1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Nac1
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Opossum
  • 免疫原

    Synthetic peptide:

    KTEQQESDSVQC

    , corresponding to internal sequence amino acids 167-178 of Human Nac1

  • ポジティブ・コントロール
    • Bone Marrow lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab60264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報Peptide ELISA: antibody detection limit dilution 1/2000.
    WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
    • 組織特異性Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
    • 配列類似性Contains 1 BEN domain.
      Contains 1 BTB (POZ) domain.
    • 細胞内局在Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BEND8 antibody
      • BTB Domain Containing 14B antibody
      • BTB/POZ domain-containing protein 14B antibody
      • btbd14b antibody
      • FLJ37383 antibody
      • NAC-1 antibody
      • NAC1 antibody
      • Nacc1 antibody
      • NACC1_HUMAN antibody
      • Nucleus accumbens-associated protein 1 antibody
      see all

    Anti-Nac1 antibody 画像

    • ab60264 antibody (0.5µg/ml) staining of Nac1 in Human Bone Marrow lysate (35µg protein in RIPA buffer)

      Predicted band size : 57 kDa
      Observed band size : 57 kDa

    Anti-Nac1 antibody (ab60264) 使用論文

    ab60264 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab60264.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"