製品の概要

  • 製品名Anti-n-Myc antibody
    n-Myc 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to n-Myc
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to Human n-Myc aa 361-410 (C terminal).
    Sequence:

    SVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPE


    Database link: P04198

  • ポジティブ・コントロール
    • Fetal heart lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab24339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能May function as a transcription factor.
  • 関連疾患Note=Amplification of the N-MYC gene is associated with a variety of human tumors, most frequently neuroblastoma, where the level of amplification appears to increase as the tumor progresses.
    Defects in MYCN are the cause of microcephaly-oculo-digito-esophageal-duodenal syndrome (MODED) [MIM:164280]; also known as oculodigitoesophagoduodenal syndrome (ODED). Microcephaly-oculo-digito-esophageal-duodenal syndrome is characterized by variable combinations of esophageal and duodenal atresias, microcephaly, learning disability and limb malformations. Cardiac and renal malformations, vertebral anomalies, and deafness have also been described.
    Defects in MYCN are the cause of microcephaly and digital abnormalities with normal intelligence (MCPHDANI) [MIM:602585].
  • 配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 発生段階Expressed during fetal development.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bHLHe37 antibody
    • Class E basic helix-loop-helix protein 37 antibody
    • MODED antibody
    • mycn antibody
    • MYCN_HUMAN antibody
    • N myc antibody
    • N myc proto oncogene protein antibody
    • N-myc proto-oncogene protein antibody
    • Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene antibody
    • Neuroblastoma MYC oncogene antibody
    • NMYC antibody
    • NMYC proto oncogene protein antibody
    • ODED antibody
    • Oncogene NMYC antibody
    • pp65/67 antibody
    • v myc avian myelocytomatosis viral related oncogene neuroblastoma derived antibody
    • v myc myelocytomatosis viral related oncogene neuroblastoma derived antibody
    see all

Anti-n-Myc antibody 画像

  • Anti-n-Myc antibody (ab24339) at 2.5 µg/ml + Fetal heart lysate

    Secondary
    HRP-conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 50 kDa
    Observed band size : 50 kDa

Anti-n-Myc antibody (ab24339) 使用論文

ab24339 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Following an alignment of the immunogen sequence with the woodchuck sequence that you have provided me with I can tell you that there was no sequence similarity and therefore I predict that this antibody would not react ...

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Thank you for your enquiry. Unfortunately the immunogen sequence used to raise n-Myc antibody (ab24339) remains proprietary. It was a synthetic peptide corresponding to a region of Human MYCN. However, if you provide me with the sequence or Swiss-Pr...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"