製品の概要

  • 製品名Anti-MYSM1 antibody
    MYSM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MYSM1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide between amino acids 118-147 from the N-terminal region of Human MYSM1 (NP_001078956.1)

  • ポジティブ・コントロール
    • MDA-MB231 cell lysate Mouse kidney tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 95 kDa.

ターゲット情報

  • 機能Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
  • 配列類似性Belongs to the peptidase M67A family. MYSM1 subfamily.
    Contains 1 MPN (JAB/Mov34) domain.
    Contains 1 SANT domain.
    Contains 1 SWIRM domain.
  • ドメインBinds double-stranded DNA via the SANT domain. The SWIRM domain does not bind double-stranded DNA.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2A-DUB antibody
    • 2ADUB antibody
    • Histone H2A deubiquitinase antibody
    • Histone H2A deubiquitinase MYSM1 antibody
    • KIAA1915 antibody
    • Myb like SWIRM and MPN domains 1 antibody
    • Myb like, SWIRM and MPN domain containing protein antibody
    • Myb like, SWIRM and MPN domains 1 antibody
    • Myb-like antibody
    • Myb-like, SWIRM and MPN domains 1 antibody
    • MYSM 1 antibody
    • mysm1 antibody
    • MYSM1 Myb-like, SWIRM and MPN domains 1 antibody
    • MYSM1_HUMAN antibody
    • RP4-592A1.1 antibody
    • SWIRM and MPN domain-containing protein 1 antibody
    see all

Anti-MYSM1 antibody 画像

  • Anti-MYSM1 antibody (ab107542) at 1/100 dilution + MDA-MB231 cell lysate at 35 µg

    Predicted band size : 95 kDa
  • Anti-MYSM1 antibody (ab107542) at 1/100 dilution + Mouse kidney tissue lysate at 35 µg

    Predicted band size : 95 kDa

Anti-MYSM1 antibody (ab107542) 使用論文

ab107542 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"