製品の概要

  • 製品名Anti-Myozenin 2 antibody
    Myozenin 2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Myozenin 2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human Myozenin 2 (AAH05195)

  • ポジティブ・コントロール
    • Myozenin 2 transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 30 kDa.

ターゲット情報

  • 機能Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
  • 組織特異性Expressed specifically in heart and skeletal muscle.
  • 関連疾患Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16) [MIM:613838]. CMH16 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
  • 配列類似性Belongs to the myozenin family.
  • 細胞内局在Cytoplasm > myofibril > sarcomere > Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C4orf5 antibody
    • Calcineurin binding protein calsarcin 1 antibody
    • Calsarcin 1 antibody
    • Calsarcin-1 antibody
    • Calsarcin1 antibody
    • CMH16 antibody
    • CS 1 antibody
    • CS1 antibody
    • FATZ related protein 2 antibody
    • FATZ-related protein 2 antibody
    • Muscle specific protein antibody
    • MYOZ 2 antibody
    • MYOZ2 antibody
    • MYOZ2_HUMAN antibody
    • Myozenin-2 antibody
    • Myozenin2 antibody
    see all

Anti-Myozenin 2 antibody 画像

  • All lanes : Anti-Myozenin 2 antibody (ab89148) at 1/500 dilution

    Lane 1 : Myozenin 2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 30 kDa
    Observed band size : 30 kDa

Anti-Myozenin 2 antibody (ab89148) 使用論文

ab89148 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89148.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"