Anti-Myosin, smooth muscle heavy chain 1 and 2 抗体 [SPM201], prediluted (ab17811)


  • 製品名Anti-Myosin, smooth muscle heavy chain 1 and 2 antibody [SPM201], prediluted
    Myosin, smooth muscle heavy chain 1 and 2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SPM201] to Myosin, smooth muscle heavy chain 1 and 2, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Crude human uterus extract

  • ポジティブ・コントロール
    • Crude human uterus extract
  • 特記事項Two isoforms: 205kDa (MHC-1) and 200kDa (MHC-2)


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
  • 精製度Whole antiserum
  • ポリ/モノモノクローナル
  • クローン名SPM201
  • アイソタイプIgG
  • 軽鎖の種類kappa
  • 研究分野


Our Abpromise guarantee covers the use of ab17811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報
    IHC-P: Working dilution: Ready-to-use for 30 min at RT
    Staining of formalin-fixed tissues REQUIRES digesting sections with trypsin at 1mg/ml PBS, 10 min at 37oC, followed by boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Muscle contraction.
    • 組織特異性Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea.
    • 関連疾患Note=A chromosomal aberration involving MYH11 is found in acute myeloid leukemia of M4EO subtype. Pericentric inversion inv(16)(p13;q22). The inversion produces a fusion protein consisting of the 165 N-terminal residues of CBF-beta (PEPB2) and the tail region of MYH11.
      Defects in MYH11 are the cause of aortic aneurysm familial thoracic type 4 (AAT4) [MIM:132900]; also known as familial thoracic aortic aneurysm and dissection (TAAD). Aneurysms and dissections of the aorta usually result from degenerative changes in the aortic wall. Thoracic aortic aneurysms and dissections are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. Patients with AAT4 show marked aortic stiffness. Pathological aortas show large areas of medial degeneration with very low smooth muscle cells content.
    • 配列類似性Contains 1 IQ domain.
      Contains 1 myosin head-like domain.
    • ドメインThe rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
      Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
    • 細胞内局在Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AAT4 antibody
      • DKFZp686D10126 antibody
      • DKFZp686D19237 antibody
      • FAA4 antibody
      • FLJ35232 antibody
      • KIAA0866 antibody
      • MGC126726 antibody
      • MGC32963 antibody
      • MYH11 antibody
      • MYH11_HUMAN antibody
      • Myosin heavy chain 11 antibody
      • Myosin heavy chain 11 smooth muscle antibody
      • Myosin heavy chain antibody
      • Myosin heavy chain smooth muscle isoform antibody
      • Myosin heavy polypeptide 11 smooth muscle antibody
      • Myosin-11 antibody
      • SM1 antibody
      • SM2 antibody
      • SMHC antibody
      • SMMHC antibody
      • smooth muscle isoform antibody
      • Smooth muscle myosin heavy chain 11 antibody
      see all

    Anti-Myosin, smooth muscle heavy chain 1 and 2 antibody [SPM201], prediluted 画像

    • Human uterus stained with anti-Myosin, (ab17811) 

    Anti-Myosin, smooth muscle heavy chain 1 and 2 antibody [SPM201], prediluted (ab17811) 使用論文

    ab17811 has not yet been referenced specifically in any publications.

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