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RabMAb

Anti-Myosin light chain 3 抗体 [EPR4161] (ab108516)

製品の概要

  • 製品名
    Anti-Myosin light chain 3 antibody [EPR4161]
    Myosin light chain 3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4161] to Myosin light chain 3
  • アプリケーション
    適用あり: WBmore details
    適用なし: Flow Cyt,ICC,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Myosin light chain 3.

  • ポジティブ・コントロール
    • Human skeletal muscle, Human heart, Mouse heart, Mouse liver, and Rat heart lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
  • 追加情報
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • ターゲット情報

    • 機能
      Regulatory light chain of myosin. Does not bind calcium.
    • 関連疾患
      Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic type 8 (CMH8) [MIM:608751]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive.
      Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 1 (MVC1) [MIM:608751]. MVC1 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
    • 配列類似性
      Contains 3 EF-hand domains.
    • 翻訳後修飾
      The N-terminus is blocked.
      N-terminus is methylated by METTL11A/NTM1.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cardiac myosin light chain 1 antibody
      • CMH8 antibody
      • CMLC1 antibody
      • ELC of myosin antibody
      • Essential light chain of myosin antibody
      • MLC1SB antibody
      • MLC1V antibody
      • MYL3 antibody
      • MYL3_HUMAN antibody
      • Myosin light chain 1 antibody
      • Myosin light chain 1 slow twitch muscle B/ventricular isoform antibody
      • Myosin light chain 1 slow, B antibody
      • Myosin light chain 3 antibody
      • Myosin, light chain 1, ventricular antibody
      • myosin, light chain 3, alkali; ventricular, skeletal, slow antibody
      • myosin, light polypeptide 3, alkali antibody
      • myosin, light polypeptide 3, alkali; ventricular, skeletal, slow antibody
      • OTTHUMP00000165922 antibody
      • Slow skeletal ventricular myosin alkali light chain 3 antibody
      • slow-twitch muscle B/ventricular isoform antibody
      • Ventricular/slow twitch myosin alkali light chain antibody
      • VLC1 antibody
      see all

    画像

    • All lanes : Anti-Myosin light chain 3 antibody [EPR4161] (ab108516) at 1/1000 dilution

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : Human heart lysate
      Lane 3 : Mouse heart lysate
      Lane 4 : Mouse liver lysate
      Lane 5 : Rat heart lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 22 kDa

    プロトコール

    参考文献

    ab108516 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab108516.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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