Anti-MyoD1 抗体 [5.2F], prediluted (ab7272)

製品の概要

  • 製品名Anti-MyoD1 antibody [5.2F], prediluted
    MyoD1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [5.2F] to MyoD1, prediluted
  • 特異性This antibody is specific to a 45 kD protein. This antibody does not react with myogenin, Myf5 or Myf6. MyoD1 stains the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue but is expressed strongly in the tumor cell nuclei of rhabdomyosarcomas.
  • アプリケーション適用あり: IHC-Frmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    BALB/C mice were injected with a recombinant mouse MyoD1 protein.

  • エピトープThis antibody is specific to an epitope of amino acid 3-56 in the N-terminus of mouse MyoD1.
  • ポジティブ・コントロール
    • Tonsil

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab7272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 機能Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
  • 配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 翻訳後修飾Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function.
    Ubiquitinated on the N-terminus; which is required for proteasomal degradation.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bHLHc1 antibody
    • Class C basic helix-loop-helix protein 1 antibody
    • MYF 3 antibody
    • Myf-3 antibody
    • MYF3 antibody
    • Myoblast determination protein 1 antibody
    • Myod 1 antibody
    • MYOD antibody
    • MYOD1 antibody
    • MYOD1_HUMAN antibody
    • Myogenic differentiation 1 antibody
    • Myogenic factor 3 antibody
    • Myogenic factor MYF 3 antibody
    • Myogenin D1 antibody
    • PUM antibody
    see all

Anti-MyoD1 antibody [5.2F], prediluted (ab7272) 使用論文

ab7272 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"