製品の概要

  • 製品名Anti-MYO1E antibody
    MYO1E 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MYO1E
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 1043-1092 of Human MYO1E (NP_004989).

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab98191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 127 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
  • 組織特異性Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes.
  • 関連疾患Focal segmental glomerulosclerosis 6
  • 配列類似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 IQ domain.
    Contains 1 myosin motor domain.
    Contains 1 SH3 domain.
    Contains 1 TH1 (class I myosin tail homology) domain.
  • 細胞内局在Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction. Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FSGS6 antibody
    • HuncM-IC antibody
    • MYO1C antibody
    • Myo1e antibody
    • MYO1E variant protein antibody
    • MYO1E_HUMAN antibody
    • Myosin heavy chain myr 3 antibody
    • Myosin IC, formerly antibody
    • Myosin IE antibody
    • Myosin-Ic antibody
    • Myr 3 antibody
    • Myr3 antibody
    • MYR5 antibody
    • Unconventional myosin 1E antibody
    • Unconventional myosin Ie antibody
    • Unconventional myosin-Ie antibody
    see all

Anti-MYO1E antibody 画像

  • Anti-MYO1E antibody (ab98191) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 127 kDa

Anti-MYO1E antibody (ab98191) 使用論文

ab98191 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"