製品の概要

  • 製品名Anti-MYO18A antibody
    MYO18A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MYO18A
  • アプリケーション適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 300-350 of human MYO18A (NP_510880.2).

  • ポジティブ・コントロール
    • RIPA whole cell lysate from HeLa cells.
  • 特記事項


    ab81689 has not performed satisfactorily when used for WB of MYO18A in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO18A.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab81689 was affinity purified using an epitope specific to MYO18A immobilized on solid support.
  • 一次抗体 備考ab81689 has not performed satisfactorily when used for WB of MYO18A in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO18A.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab81689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 関連性Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE) rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid associated lung collectin that mediates innate and adaptive immune responses in the lungs.
    • 細胞内局在Isoform 1: Endoplasmic reticulum Golgi intermediate compartment. Cytoplasm, cytoskeleton. Note: Colocalizes with actin. Isoform 2: Cytoplasm. Note: Lacks the PDZ domain. Diffusely localized in the cytoplasm.
    • 参照データベース
    • 別名
      • MAJN antibody
      • Molecule associated with JAK3 N terminus antibody
      • Myosin 18A antibody
      • Myosin containing a PDZ domain antibody
      • Myosin XVIIIA antibody
      • MyoXVIIIIA antibody
      • MYSPDZ antibody
      • SPR210 antibody
      see all

    Anti-MYO18A antibody 画像

    • Detection of human MYO18A by Western Blot of Immunoprecipitates.
      Samples: RIPA whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.
      ab81689 used for IP at 3 µg/mg lysate (lane 1).
      MYO18A was also immunoprecipitated using anti MYO18A (ab81690), which recognizes a downstream epitope (lane 2).
      Lane 3 represents the control IgG.
      For blotting immunoprecipitates, ab81689 was used at 1 µg/ml.
      Detection: by Chemiluminescence with an exposure time of 1 second.

    Anti-MYO18A antibody (ab81689) 使用論文

    ab81689 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"