Anti-Myeloperoxidase 抗体 [8F4] (ab16886)

製品の概要

  • 製品名Anti-Myeloperoxidase antibody [8F4]
    Myeloperoxidase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8F4] to Myeloperoxidase
  • アプリケーション適用あり: IHC-Fr, Flow Cytmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Purified mouse Myeloperoxidase from WEHI-3 cells.

  • ポジティブ・コントロール
    • Neutrophils isolated from digested infarcts

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab16886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/10.
Flow Cyt 1/10. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
  • 関連疾患Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
  • 配列類似性Belongs to the peroxidase family. XPO subfamily.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 84 kDa myeloperoxidase antibody
    • 89 kDa myeloperoxidase antibody
    • EC 1.11.1.7 antibody
    • EC1.11.2.2 antibody
    • fj80f04 antibody
    • MPO antibody
    • mpx antibody
    • myeloid-specific peroxidase antibody
    • Myeloperoxidase antibody
    • Myeloperoxidase heavy chain antibody
    • Myeloperoxidase light chain antibody
    • PERM_HUMAN antibody
    • wu:fj80f04 antibody
    see all

Anti-Myeloperoxidase antibody [8F4] (ab16886) 使用論文

This product has been referenced in:
  • Lu SM  et al. HIV-1 Tat-Induced Microgliosis and Synaptic Damage via Interactions between Peripheral and Central Myeloid Cells. PLoS One 6:e23915 (2011). IHC-FoFr ; Mouse . Read more (PubMed: 21912650) »
  • Salguero Palacios R  et al. Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice. Lab Invest 88:1192-203 (2008). IHC-Fr ; Mouse . Read more (PubMed: 18794850) »

See all 2 Publications for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Rat Cell lysate - whole cell (Rat Neutrophils and Human MPO)
Loading amount 6 µg
Specification Rat Neutrophils and Human MPO
Gel Running Conditions Reduced Denaturing (7.5)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5.0% · Temperature: 23°C
Username

Mrs. Donna Flanagan

Verified customer

投稿 Mar 13 2009

As far as we know, the epitope has not been mapped. Please contact us again if you have any additional questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"