Biotin Anti-Myeloperoxidase 抗体 [2D4] (ab90811)
Key features and details
- Biotin Mouse monoclonal [2D4] to Myeloperoxidase
- Suitable for: IHC-Fr, ICC/IF, IHC-P, Flow Cyt
- Reacts with: Mouse, Rat
- Conjugation: Biotin
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Biotin Anti-Myeloperoxidase antibody [2D4]
Myeloperoxidase 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [2D4] to Myeloperoxidase -
由来種
Mouse -
標識
Biotin -
アプリケーション
適用あり: IHC-Fr, ICC/IF, IHC-P, Flow Cytmore details -
種交差性
交差種: Mouse, Rat -
免疫原
Purified Rat Myeloperoxidase
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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特記事項(精製)
ab90811 is 0.2 µm filtered -
ポリ/モノ
モノクローナル -
クローン名
2D4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Assay kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab90811の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration. PubMed: 23817216
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Flow Cyt |
Use at an assay dependent concentration.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. PubMed: 23817216 |
Flow Cyt
Use at an assay dependent concentration. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
関連疾患
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
配列類似性
Belongs to the peroxidase family. XPO subfamily. -
細胞内局在
Lysosome. - Information by UniProt
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参照データベース
- Entrez Gene: 17523 Mouse
- Entrez Gene: 303413 Rat
- SwissProt: P11247 Mouse
- Unigene: 4668 Mouse
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別名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab90811 は 2 報の論文で使用されています。
- Ramachandran M et al. An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors. Mol Ther 21:2008-18 (2013). IHC-P ; Mouse . PubMed: 23817216
- Deng Z et al. Plant homologue constitutive photomorphogenesis 9 (COP9) signalosome subunit CSN5 regulates innate immune responses in macrophages. Blood 117:4796-804 (2011). IHC ; Mouse . PubMed: 21403132