製品の概要

  • 製品名Anti-Myeloperoxidase antibody [1A1]
    Myeloperoxidase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1A1] to Myeloperoxidase
  • アプリケーション適用あり: IP, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native protein purified from Human sputum

  • ポジティブ・コントロール
    • HL-60 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at an assay dependent dilution. Use 2µg for 400µl lysate.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
  • 関連疾患Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
  • 配列類似性Belongs to the peroxidase family. XPO subfamily.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 84 kDa myeloperoxidase antibody
    • 89 kDa myeloperoxidase antibody
    • EC 1.11.1.7 antibody
    • EC1.11.2.2 antibody
    • fj80f04 antibody
    • MPO antibody
    • mpx antibody
    • myeloid-specific peroxidase antibody
    • Myeloperoxidase antibody
    • Myeloperoxidase heavy chain antibody
    • Myeloperoxidase light chain antibody
    • PERM_HUMAN antibody
    • wu:fj80f04 antibody
    see all

Anti-Myeloperoxidase antibody [1A1] 画像

  • Immunoprecipitation analysis of HL-60 cell lysate with ab51065 at 2µg for 400µl of lysate. Lane 1: Input; Lane 2: Precipitates. Western blot detection was done with ab76100.

Anti-Myeloperoxidase antibody [1A1] (ab51065) 使用論文

This product has been referenced in:
  • Silvescu CI & Sackstein R G-CSF induces membrane expression of a myeloperoxidase glycovariant that operates as an E-selectin ligand on human myeloid cells. Proc Natl Acad Sci U S A 111:10696-701 (2014). IP ; Human . Read more (PubMed: 25002508) »
  • Huang Y  et al. Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest 123:3815-28 (2013). IP ; Human . Read more (PubMed: 23908111) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"