Anti-Muscarinic Acetylcholine Receptor M5 抗体 (ab41171)


  • 製品名
    Anti-Muscarinic Acetylcholine Receptor M5 antibody
    Muscarinic Acetylcholine Receptor M5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5 - Carboxyterminal end
  • 由来種
  • 特異性
    Cross reactivity: M5 Muscarinic Receptor (519-531): 100% M5 Muscarinic Receptor: 75% No cross reactivity was observed in: M1 Muscarinic Receptor(451-460) M1 Muscarinic Receptor M2 Muscarinic Receptor(457-466) M2 Muscarinic Receptor M3 Muscarinic Receptor(580-589) M3 Muscarinic Receptor M4 Muscarinic Receptor(469-478) M4 Muscarinic Receptor
  • アプリケーション
    適用あり: WB, ELISA, IHC (PFA fixed), IHC-FoFrmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic peptide analogue of the C terminal of rat muscarinic M5 receptor covalently attached onto a carrier protein.

  • ポジティブ・コントロール
    • Rat brain tissue, whole brain homogenate and cultured cells.


  • 製品の状態
    Lyophilised:Reconstitute the lyophilized pooled antisera with 0.1 ml of 10 mg/ml BSA and 0.01% Sodium Azide in PBS for the equivalent of whole antisera, or with additional buffer for more dilute antisera.
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • Concentration information loading...
  • 精製度
    Whole antiserum
  • ポリ/モノ
  • アイソタイプ
  • 研究分野


Our Abpromise guarantee covers the use of ab41171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/400. Predicted molecular weight: 60 kDa. Blocking with 5% goat or donkey serum significantly reduces background when compared with BSA or milk blocking.
ELISA Use at an assay dependent concentration.
IHC (PFA fixed) 1/400.
IHC-FoFr Use at an assay dependent concentration. PubMed: 23773170


  • 関連性
    The muscarinic acetylcholine receptor M5 is a member of the GPCR family (subfamily, acetylcholine) which mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. The rimary transducing effect is PI turnover. The receptor has been reported to be expressed in blood, brain, and ovary. ESTs have been isolated from human testis and placenta libraries.
  • 細胞内局在
    Membrane; multi-pass membrane protein.
  • 参照データベース
  • 別名
    • Acetylcholine receptor muscarinic 5 antibody
    • AChR antibody
    • AChR M5 antibody
    • CHKM5MR antibody
    • Cholinergic receptor muscarinic 5 antibody
    • Chrm 5 antibody
    • CHRM5 antibody
    • HM 5 antibody
    • HM5 antibody
    • m5 antibody
    • M5R antibody
    • MGC41838 antibody
    see all


This product has been referenced in:
  • Zhu H  et al. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun 8:1676 (2017). Read more (PubMed: 29162816) »
  • Muschter D  et al. Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis. Arthritis Res Ther 17:169 (2015). IF . Read more (PubMed: 26104678) »

See all 4 Publications for this product

レビューと Q&A

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I have not been able to obtain any images of this antibody using in tissue staining, and I am sorry that we don't have these available. <...

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Thank you for contacting us with your question.

I've looked through our records andto our knowledge, the antibody has only been tested inWestern blot, ELISA, and IHC on standard PFA-fixed tissue. I will get in touch with the lab and request i...

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