Anti-Muscarinic Acetylcholine Receptor 2 抗体 (ab41168)

製品の概要

  • 製品名Anti-Muscarinic Acetylcholine Receptor 2 antibody
    Muscarinic Acetylcholine Receptor 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Muscarinic Acetylcholine Receptor 2
  • 特異性M2 Muscarinic Receptor (457-466): 100% M2 Muscarinic Receptor: 50% No cross reactivity with M1, M3, M4 and M5 Muscarinic Receptors.
  • アプリケーション適用あり: WB, ICC/IF, ELISAmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic peptide corresponding to C-terminal region (Rat) covalently attached onto a carrier protein.

  • ポジティブ・コントロール
    • PLP fixed rat brain section; whole rat brain homogenate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab41168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ICC/IF
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    ICC/IF: 1/5000. Fix with PLP.
    WB: 1/1000. Predicted molecular weight: 52 kDa.

    With this antibody, we have found that blocking with 5% goat or donkey serum significantly reduces background as compared to BSA or milk.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.
    • 関連疾患Genetic variations in CHRM2 can influence susceptibility to major depressive disorder (MDD) [MIM:608516]. MDD is one of the most common psychiatric disorders. MDD is a complex trait characterized by one or more major depressive episodes without a history of manic, mixed, or hypomanic episodes. A major depressive episode is characterized by at least 2 weeks during which there is a new onset or clear worsening of either depressed mood or loss of interest or pleasure in nearly all activities. Four additional symptoms must also be present including changes in appetite, weight, sleep, and psychomotor activity; decreased energy; feelings of worthlessness or guilt; difficulty thinking, concentrating, or making decisions; or recurrent thoughts of death or suicidal ideation, plans, or attempts. The episode must be accompanied by distress or impairment in social, occupational, or other important areas of functioning.
    • 配列類似性Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.
    • 細胞内局在Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 7TM receptor antibody
      • Acetylcholine receptor, muscarinic, 2 antibody
      • AChR antibody
      • Acm2 antibody
      • ACM2_HUMAN antibody
      • Cholinergic receptor muscarinic 2 antibody
      • Cholinergic receptor, muscarinic 2, cardiac antibody
      • Cholinergic receptor, muscarinic 2, isoform a antibody
      • Cholinergic receptor, muscarinic 2a antibody
      • CHRM 2 antibody
      • CHRM2 antibody
      • chrm2a antibody
      • CM2 antibody
      • FLJ43243 antibody
      • HM 2 antibody
      • HM2 antibody
      • M2 antibody
      • M2 muscarinic receptor antibody
      • M2-mAChR antibody
      • MGC120006 antibody
      • MGC120007 antibody
      • Muscarinic acetylcholine receptor M2 antibody
      • Muscarinic M2 receptor antibody
      see all

    Anti-Muscarinic Acetylcholine Receptor 2 antibody (ab41168) 使用論文

    ab41168 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab41168.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"