Anti-muscarinic Acetylcholine Receptor 1 抗体 (ab77098)

製品の概要

  • 製品名Anti-muscarinic Acetylcholine Receptor 1 antibody
    Muscarinic Acetylcholine Receptor 1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to muscarinic Acetylcholine Receptor 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog, Pig, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide:

    C-DKRRWRKIPKRPGSVH

    , corresponding to C terminal amino acids 438-453 of human muscarinic Acetylcholine Receptor 1 (NP_000729.2).

  • ポジティブ・コントロール
    • Human brain lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab77098 is purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.

ターゲット情報

  • 関連性The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.
  • 細胞内局在Cell Membrane; multi-pass membrane protein
  • 参照データベース
  • 別名
    • AChR antibody
    • Cholinergic receptor muscarinic 1 antibody
    • CHRM1 antibody
    • HM1 antibody
    • M1 antibody
    • Muscarinic acetylcholine receptor M1 antibody
    see all

Anti-muscarinic Acetylcholine Receptor 1 antibody 画像

  • Anti-muscarinic Acetylcholine Receptor 1 antibody (ab77098) at 0.300000011921 µg/ml + human brain lysate (in RIPA buffer) at 35 µg

    Predicted band size : 51 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

Anti-muscarinic Acetylcholine Receptor 1 antibody (ab77098) 使用論文

ab77098 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"