製品の概要

  • 製品名Anti-MUM1 antibody
    MUM1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to MUM1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human protein

  • ポジティブ・コントロール
    • FLJ14868-transfected 293T cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab69220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

ターゲット情報

  • 機能Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
  • 配列類似性Belongs to the MUM1 family.
    Contains 1 PWWP domain.
  • ドメインThe PWWP domain mediates the interaction with nucleosomes.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus. Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EXPAND1 antibody
    • FLJ14868 antibody
    • FLJ22283 antibody
    • HSPC211 antibody
    • Melanoma associated antigen (mutated) 1 antibody
    • Melanoma ubiquitous mutated protein antibody
    • MGC131891 antibody
    • MGC163315 antibody
    • MUM 1 antibody
    • MUM-1 antibody
    • MUM1 antibody
    • MUM1_HUMAN antibody
    • Mutated melanoma associated antigen 1 antibody
    • Mutated melanoma-associated antigen 1 antibody
    • Protein expandere antibody
    • PWWP domain containing protein MUM1 antibody
    • PWWP domain-containing protein MUM1 antibody
    see all

Anti-MUM1 antibody 画像

  • All lanes : Anti-MUM1 antibody (ab69220) at 1/500 dilution

    Lane 1 : MUM1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 79 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-MUM1 antibody (ab69220) 使用論文

ab69220 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab69220.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"