製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MUC20
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C terminal region of Human MUC20 (UniProt ID: Q86ST8).

  • ポジティブ・コントロール
    • WiDr cell line lysates

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab113091 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab113091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 72 kDa.

ターゲット情報

  • 機能
    May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
  • 組織特異性
    Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
  • 細胞内局在
    Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MUC 20 antibody
    • MUC-20 antibody
    • Muc20 antibody
    • MUC20_HUMAN antibody
    • Mucin 20 antibody
    • Mucin 20, cell surface associated antibody
    • Mucin-20 antibody
    • Transmembrane mucin MUC20S antibody
    see all

画像

  • Anti-MUC20 antibody (ab113091) at 1/100 dilution + WiDr cell line lysates at 35 µg

    Predicted band size : 72 kDa

プロトコール

参考文献

ab113091 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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