製品の概要

  • 製品名
    Anti-MUC17 antibody
  • 製品の詳細
    Rabbit polyclonal to MUC17
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 4122-4262 of Human MUC17.

  • ポジティブ・コントロール
    • Human small intestine tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab122184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Probably plays a role in maintaining homeostasis on mucosal surfaces.
  • 組織特異性
    Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.
  • 配列類似性
    Contains 1 EGF-like domain.
    Contains 1 SEA domain.
  • 翻訳後修飾
    Probably cleaved within the SEA domain.
    N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated.
  • 細胞内局在
    Cell membrane and Secreted. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Membrane mucin MUC17 antibody
    • MUC-17 antibody
    • MUC-3 antibody
    • MUC17 antibody
    • MUC17_HUMAN antibody
    • Mucin 17, cell surface associated antibody
    • Mucin-17 antibody
    • Secreted mucin MUC17 antibody
    • Small intestinal mucin MUC3 antibody
    • Small intestinal mucin-3 antibody
    see all

画像

  • ab122184 at 1/20 dilution staining MUC17 in Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

プロトコール

参考文献

This product has been referenced in:
  • Yang CW  et al. Genetic variations of MUC17 are associated with endometriosis development and related infertility. BMC Med Genet 16:60 (2015). IHC . Read more (PubMed: 26285705) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab122184.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録