The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報WB: Use at a concentration of 0.25 - 0.5 µg/ml. Detects bands of approximately 55 ,27 and 29 kDa (predicted molecular weight: 55 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
組織特異性Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.
翻訳後修飾Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated.
細胞内局在Cell membrane. Secreted. Also exists as a soluble form.