製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MTUS1
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide coresponding to a region between amino acids 450-500 of Human MTUS1 (NP_001001924.1)

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報
    Is unsuitable for WB.
  • ターゲット情報

    • 関連性
      Multiple alternatively spliced transcript variants encoding different isoforms have been found for the MTUS1 (Mitochondrial tumor suppressor 1) gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and cooperates with the angiotension II (AT2) receptor (AGTR2) to inhibit ERK2 activation and cell proliferation. MTUS1 polypeptides are identical in their carboxy-terminal region carrying four coiled-coil domains. In their amino-terminal portion, MTUS1 polypeptides exhibit distinct motifs for localisation in the cytosol, nucleus or cell membrane, suggesting that MTUS1 gene products may be involved in a variety of intracellular functions in an AT2-dependent and independent manner.
    • 細胞内局在
      Cell Membrane, Golgi Apparatus, Mitochondrial and Nuclear. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
    • 参照データベース
    • 別名
      • AGTR2-interacting protein antibody
      • Angiotensin II type 2 receptor interacting protein antibody
      • AT2 receptor interacting protein antibody
      • AT2 receptor-binding protein antibody
      • AT2R binding protein antibody
      • ATBP antibody
      • ATIP antibody
      • ATIP1 antibody
      • DKFZp586D1519 antibody
      • DKFZp686F20243 antibody
      • Erythroid differentiation related antibody
      • FLJ14295 antibody
      • GK 1 antibody
      • GK1 antibody
      • KIAA1288 antibody
      • Microtubule associated tumor suppressor 1 antibody
      • Mitochondrial tumor suppressor 1 antibody
      • Mitochondrial tumor suppressor gene 1 antibody
      • MP 44 antibody
      • MP44 antibody
      • MTSG 1 antibody
      • MTSG1 antibody
      • MTUS 1 antibody
      • Transcription factor MTSG1 antibody
      see all

    画像

    • ab113979, used for IP at 3 µg/mg lysate, staining MTUS1 in HeLa whole cell lysate (1 mg for IP, 20% of IP loaded).

      Detection: Chemiluminescence with an exposure time of 30 seconds.

    プロトコール

    参考文献

    ab113979 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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