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RabMAb

Anti-mTOR (phospho S2448) 抗体 [EPR426(2)] (ab109268)

ab109268 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab109268 は 50 報の論文で使用されています。

  • Katreddy RR  et al. Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt. Oncogenesis 7:5 (2018). PubMed: 29358623
  • Zhou L  et al. miR-185 Inhibits Fibrogenic Activation of Hepatic Stellate Cells and Prevents Liver Fibrosis. Mol Ther Nucleic Acids 10:91-102 (2018). PubMed: 29499960
  • Chen YQ  et al. Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human ?dT cells against colon cancer. Exp Cell Res 362:63-71 (2018). PubMed: 29104081
  • Jin X  et al. HO-1/EBP interaction alleviates cholesterol-induced hypoxia through the activation of the AKT and Nrf2/mTOR pathways and inhibition of carbohydrate metabolism in cardiomyocytes. Int J Mol Med 39:1409-1420 (2017). PubMed: 28487965
  • Zhu H  et al. IDH1 R132H Mutation Enhances Cell Migration by Activating AKT-mTOR Signaling Pathway, but Sensitizes Cells to 5-FU Treatment as NADPH and GSH Are Reduced. PLoS One 12:e0169038 (2017). WB ; Human . PubMed: 28052098
  • Huang G  et al. Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway. Int J Mol Med 39:559-568 (2017). Human . PubMed: 28112381
  • Wang Z  et al. Clinicopathological signature of p21-activated kinase 1 in prostate cancer and its regulation of proliferation and autophagy via the mTOR signaling pathway. Oncotarget 8:22563-22580 (2017). WB, IHC-P ; Human . PubMed: 28186966
  • Tian Y  et al. Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways. Front Mol Neurosci 10:190 (2017). WB ; Mouse . PubMed: 28663724
  • Wang Z  et al. Knockdown of STMN1 enhances osteosarcoma cell chemosensitivity through inhibition of autophagy. Oncol Lett 13:3465-3470 (2017). PubMed: 28529574
  • Fu S  et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep 7:43771 (2017). PubMed: 28256562
  • Li Y  et al. MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. Cell Mol Biol Lett 22:3 (2017). WB . PubMed: 28536634
  • Lin Q  et al. Cisplatin regulates cell autophagy in endometrial cancer cells via the PI3K/AKT/mTOR signalling pathway. Oncol Lett 13:3567-3571 (2017). PubMed: 28521459
  • Zhang D  et al. Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway. Int J Oncol 50:1513-1530 (2017). WB ; Human . PubMed: 28339091
  • Li H  et al. MEN1/Menin regulates milk protein synthesis through mTOR signaling in mammary epithelial cells. Sci Rep 7:5479 (2017). PubMed: 28710500
  • Cao Y  et al. Ginsenoside Rg3 inhibits angiogenesis in a rat model of endometriosis through the VEGFR-2-mediated PI3K/Akt/mTOR signaling pathway. PLoS One 12:e0186520 (2017). PubMed: 29140979
  • Guo JN  et al. Activation of the Akt/mTOR signaling pathway: A potential response to long-term neuronal loss in the hippocampus after sepsis. Neural Regen Res 12:1832-1842 (2017). IHC-P ; Mouse . PubMed: 29239329
  • Prieto-Domínguez N  et al. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1a and hypoxia-mediated mitophagy. Oncotarget 8:91402-91414 (2017). PubMed: 29207653
  • Zeng X  et al. Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells. Oncotarget 8:72872-72885 (2017). PubMed: 29069832
  • Wu J  et al. High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction. Oncotarget 8:40843-40856 (2017). PubMed: 28489581
  • Fang Y  et al. TFE3 regulates renal adenocarcinoma cell proliferation via activation of the mTOR pathway. Mol Med Rep 16:2721-2725 (2017). PubMed: 28713889
  • Song B  et al. Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis. Mol Med Rep 16:3958-3964 (2017). PubMed: 28731147
  • Zou B  et al. Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3. Oncol Rep 38:1431-1441 (2017). PubMed: 28714011
  • Li Z  et al. Anti-Oxidative Stress Activity Is Essential for Amanita caesarea Mediated Neuroprotection on Glutamate-Induced Apoptotic HT22 Cells and an Alzheimer's Disease Mouse Model. Int J Mol Sci 18:N/A (2017). PubMed: 28749416
  • Yang L  et al. The role of mTOR signaling pathway on cognitive functions in cerebral ischemia-reperfusion. Exp Ther Med 14:2839-2844 (2017). PubMed: 28912846
  • Liang Y  et al. MicroRNA-320 regulates autophagy in retinoblastoma by targeting hypoxia inducible factor-1a. Exp Ther Med 14:2367-2372 (2017). PubMed: 28962169
  • Xu J  et al. L-3-n-Butylphthalide Activates Akt/mTOR Signaling, Inhibits Neuronal Apoptosis and Autophagy and Improves Cognitive Impairment in Mice with Repeated Cerebral Ischemia-Reperfusion Injury. Neurochem Res 42:2968-2981 (2017). WB . PubMed: 28620824
  • Yu YX  et al. Silencing of advanced glycosylation and glycosylation and product-specific receptor (RAGE) inhibits the metastasis and growth of non-small cell lung cancer. Am J Transl Res 9:2760-2774 (2017). WB ; Human . PubMed: 28670367
  • Chen Y  et al. FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell. Biochem Biophys Res Commun N/A:N/A (2016). WB ; Human . PubMed: 26993162
  • Gao B  et al. Eicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cells. Cell Death Dis 7:e2235 (2016). WB ; Mouse . PubMed: 27228350
  • Zhang L  et al. Reprogramming towards anabolism impedes degeneration in a preclinical model of retinitis pigmentosa. Hum Mol Genet N/A:N/A (2016). PubMed: 27516389
  • Fan G  et al. Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling. J Cell Mol Med 20:1908-19 (2016). Rat . PubMed: 27385290
  • Yao CJ  et al. Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. Evid Based Complement Alternat Med 2016:5989681 (2016). WB ; Human . PubMed: 28074102
  • Li XJ  et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-?B signaling pathways in osteoprotegerin knockout mice. Int J Mol Med N/A:N/A (2016). WB ; Mouse . PubMed: 27840967
  • Sun H  et al. Resistance of glioma cells to nutrient-deprived microenvironment can be enhanced by CD133-mediated autophagy. Oncotarget 7:76238-76249 (2016). WB ; Rat . PubMed: 27780926
  • Wang J  et al. Investigations on the antifatigue and antihypoxic effects of Paecilomyces hepiali extract. Mol Med Rep 13:1861-8 (2016). PubMed: 26717979
  • Yang Z  et al. Infiltrating macrophages increase RCC epithelial mesenchymal transition (EMT) and stem cell-like populations via AKT and mTOR signaling. Oncotarget 7:44478-44491 (2016). PubMed: 27283897
  • Perez SE  et al. Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aß and tau pathology. J Neuropathol Exp Neurol 74:345-58 (2015). PubMed: 25756588
  • Wiersma VR  et al. The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux. Autophagy 11:1373-88 (2015). WB . PubMed: 26086204
  • Duan Y  et al. Effects of tonic immobility (TI) and corticosterone (CORT) on energy status and protein metabolism in pectoralis major muscle of broiler chickens. Comp Biochem Physiol A Mol Integr Physiol 169:90-5 (2014). Chicken . PubMed: 24389091
  • Vallejo D  et al. Autophagic response in the Rabbit Hemorrhagic Disease, an animal model of virally-induced fulminant hepatic failure. Vet Res 45:15 (2014). WB ; Rabbit . PubMed: 24490870
  • Li C  et al. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS One 9:e101526 (2014). WB ; Human . PubMed: 24992302
  • Chikh A  et al. iASPP is a novel autophagy inhibitor in keratinocytes. J Cell Sci 127:3079-93 (2014). PubMed: 24777476
  • Chen Y  et al. Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways. Int Immunopharmacol 21:447-55 (2014). PubMed: 24905636
  • Picard M  et al. Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming. Proc Natl Acad Sci U S A 111:E4033-42 (2014). WB . PubMed: 25192935
  • Chung CH  et al. Butein Inhibits Angiogenesis of Human Endothelial Progenitor Cells via the Translation Dependent Signaling Pathway. Evid Based Complement Alternat Med 2013:943187 (2013). WB ; Rat . PubMed: 23840271
  • Xu MY  et al. Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. Food Chem Toxicol 59:703-8 (2013). Human . PubMed: 23850994
  • Hao J  et al. Phospho-mTOR: a novel target in regulation of renal lipid metabolism abnormality of diabetes. Exp Cell Res 319:2296-306 (2013). Rat . PubMed: 23827786
  • Liu SC  et al. Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance. J Clin Invest 123:5269-83 (2013). IHC ; Human . PubMed: 24270418
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Wang XQ  et al. The differential proliferative ability of satellite cells in Lantang and Landrace pigs. PLoS One 7:e32537 (2012). WB ; Pig . PubMed: 22427853

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