製品の概要

  • 製品名Anti-MTGR1 antibody [CBF5I134]
    MTGR1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CBF5I134] to MTGR1
  • アプリケーション適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant human CBFA2T2 fragment

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, 8mM Sodium phosphate, 3mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)ab51311 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
  • ポリ/モノモノクローナル
  • クローン名CBF5I134
  • アイソタイプIgG1
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab51311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50. Detects a band of approximately 59 kDa (predicted molecular weight: 67 kDa).
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
  • 組織特異性Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus.
  • 配列類似性Belongs to the CBFA2T family.
    Contains 1 MYND-type zinc finger.
    Contains 1 TAFH (NHR1) domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AML1 MTG8 antibody
    • cbfa2t2 antibody
    • Core binding factor runt domain alpha subunit 2 translocated to 2 antibody
    • core-binding factor, runt domain, alpha subunit 2 antibody
    • DKFZp313F2116 antibody
    • EHT antibody
    • ETO homolog on chromosome 20 antibody
    • ETO homologous on chromosome 20 antibody
    • MTG 8 like protein antibody
    • MTG 8 related protein 1 antibody
    • MTG8 like protein antibody
    • MTG8 related protein 1 antibody
    • MTG8-like protein antibody
    • MTG8-related protein 1 antibody
    • MTG8R_HUMAN antibody
    • MTGR 1 antibody
    • Myeloid translocation gene related protein 1 antibody
    • Myeloid translocation related protein 1 antibody
    • Myeloid translocation-related protein 1 antibody
    • p85 antibody
    • Protein CBFA2T2 antibody
    • ZMYND 3 antibody
    • ZMYND3 antibody
    see all

Anti-MTGR1 antibody [CBF5I134] 画像

  • Anti-MTGR1 antibody [CBF5I134] (ab51311) at 1/50 dilution + HeLa whole cell lysate at 25 µg

    Secondary
    anti-mouse IgG at 1/2500 dilution
    Developed using the ECL technique

    Predicted band size : 67 kDa
    Observed band size : 59 kDa (why is the actual band size different from the predicted?)

Anti-MTGR1 antibody [CBF5I134] (ab51311) 使用論文

ab51311 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"