製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MTA1
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region within residues 400 and 450 of human MTA1 (SwissProt entry Q13330).

  • ポジティブ・コントロール
    • Human stomach adenocarcinoma; human lung non small cell carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. The use of citrate buffer will enhance staining.

ターゲット情報

  • 機能
    May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
  • 組織特異性
    Widely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
  • 配列類似性
    Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • 発生段階
    Highly expressed in metastatic cells.
  • ドメイン
    Isoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
  • 細胞内局在
    Cytoplasm and Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Metastasis associated 1 antibody
    • Metastasis associated gene 1 antibody
    • Metastasis associated gene 1 protein antibody
    • Metastasis associated protein antibody
    • Metastasis associated protein MTA 1 antibody
    • Metastasis associated protein MTA1 antibody
    • Metastasis-associated protein MTA1 antibody
    • MTA 1 antibody
    • MTA1 antibody
    • MTA1_HUMAN antibody
    see all

画像

  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human stomach adenocarcinoma tissue by Immunohistochemistry. Detection: DAB staining.
  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human lung non small cell carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

プロトコール

参考文献

This product has been referenced in:
  • Agboola AO  et al. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathol Res Pract N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24176171) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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