製品の概要

  • 製品名MRS 2211
  • 製品の詳細
    Selective, competitive P2Y13 antagonist
  • 生理活性の詳細Selective, competitive P2Y13 antagonist (pA2 = 6.3). Displays >20-fold selectivity over P2Y1 and P2Y12 (IC50 > 10 μM for inhibition of human P2Y1 and human P2Y12 receptor-mediated phospholipase C responses).
  • 精製度> 95%

製品の特性

    MRS 2211 (ab120445) 使用論文

    This product has been referenced in:
    • Jacobson KA  et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal 5:75-89 (2009). Read more (PubMed: 18600475) »
    • Carrasquero LM  et al. P2X7 and P2Y13 purinergic receptors mediate intracellular calcium responses to BzATP in rat cerebellar astrocytes. J Neurochem 110:879-89 (2009). Read more (PubMed: 19457067) »
    • von Kügelgen I Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol Ther 110:415-32 (2006). Read more (PubMed: 16257449) »
    • Kim YC  et al. Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor. Biochem Pharmacol 70:266-74 (2005). Read more (PubMed: 15913566) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120445.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"