製品の概要

  • 製品名Anti-MRP8 + MRP14 antibody (Biotin)
    MRP8 + MRP14 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to MRP8 + MRP14 (Biotin)
  • 標識Biotin
  • 特異性Does not discriminate between the individual subunits MRP8 or MRP14.
  • アプリケーション適用あり: ELISA, IHC-Fr, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant MRP8/14 heterocomplex (Human). The antigen is produced by the Ca2+ dependent heterocomplex formation of MRP8 (S100A8 or Calgranulin A) and MRP14 (S100A9 or Calgranulin B), two calcium binding proteins of the S 100 protein family.

  • ポジティブ・コントロール
    • Human tonsil.
  • 特記事項Peripheral blood monocytes carry the antigen extra and intracellularly, neutrophils only intracellularly. The antigen is present on macrophages in the red pulp of the spleen and in the liver. It is also strongly expressed on macrophages in acute inflamed tissues (peridontitis, contact excema, urticaria, erythrodermia).


    In immune histochemistry, this antibody detects early inflammatory macrophages and can thus be used for the classification of acute stage inflammation in tissue sections and in smears.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: Kathon
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度IgY fraction
  • 特記事項(精製)Purified from egg yolk by repeated precipitation.
  • 一次抗体 備考In immune histochemistry, this antibody detects early inflammatory macrophages and can thus be used for the classification of acute stage inflammation in tissue sections and in smears.
  • ポリ/モノポリクローナル
  • アイソタイプIgY
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab51863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
IHC-Fr Use a concentration of 1 µg/ml.

1/1000.

IHC-P Use a concentration of 4 µg/ml.

1/250. Proteinase K pretreatment for antigen retrieval is recommended.

ターゲット情報

  • 関連性MRP8 and MRP14 are members of the S100 family of proteins containing 2 EF hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.
  • 細胞内局在Cytoplasmic and Nuclear
  • 参照データベース
  • 別名
    • CAGA antibody
    • CAGB antibody
    • Calgranulin A antibody
    • Calgranulin B antibody
    • Calprotectin L1L subunit antibody
    • CFAG antibody
    • CP10 antibody
    • Cystic fibrosis antigen antibody
    • Leukocyte L1 complex light chain antibody
    • Macrophage L1 protein Calprotectin antibody
    • Migration inhibitory factor related protein 14 antibody
    • Migration inhibitory factor related protein 8 antibody
    • MRP-14 antibody
    • MRP-8 antibody
    • P14 antibody
    • P8 antibody
    • S100 calcium binding protein A8 antibody
    • S100 calcium binding protein A9 antibody
    • S100A8 antibody
    • S100A9 antibody
    • Urinary stone protein band A antibody
    see all

Anti-MRP8 + MRP14 antibody (Biotin) 画像

  • ab51863 at 4µg/ml staining human spleen; paraffin embedded.

Anti-MRP8 + MRP14 antibody (Biotin) (ab51863) 使用論文

This product has been referenced in:
  • Lood C  et al. Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus. Arthritis Res Ther 13:R60 (2011). ELISA . Read more (PubMed: 21492422) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"