Anti-MRP8 抗体 [CF-145] (Biotin) (ab114050)

製品の概要

  • 製品名
    Anti-MRP8 antibody [CF-145] (Biotin)
    MRP8 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CF-145] to MRP8 (Biotin)
  • 標識
    Biotin
  • 特異性
    ab114050 is specific to MRP8.
  • アプリケーション
    適用あり: Flow Cyt, WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified granulocyte antigen of Human origin.

  • ポジティブ・コントロール
    • Human peripheral blood leukocytes

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% PBS
  • Concentration information loading...
  • ポリ/モノ
    モノクローナル
  • クローン名
    CF-145
  • ミエローマ
    NS0
  • アイソタイプ
    IgG2b
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab114050 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.5µg for 106 cells. ab18418-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
  • 組織特異性
    Expressed by macrophages in chronic inflammations. Also expressed in epithelial cells constitutively or induced during dermatoses.
  • 配列類似性
    Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • 細胞内局在
    Secreted. Cytoplasm. Cytoplasm > cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 60B8Ag antibody
    • AI323541 antibody
    • B8Ag antibody
    • BEE11 antibody
    • CAGA antibody
    • Calgranulin-A antibody
    • Calprotectin L1L subunit antibody
    • Calprotectin, included antibody
    • CFAG antibody
    • CGLA antibody
    • Chemotactic cytokine CP-10 antibody
    • CP-10 antibody
    • Cystic fibrosis antigen antibody
    • L1Ag antibody
    • Leukocyte L1 complex light chain antibody
    • MA387 antibody
    • MIF antibody
    • Migration inhibitory factor-related protein 8 antibody
    • MRP-8 antibody
    • Myeloid-related protein 8 antibody
    • Neutrophil cytosolic 7 kDa protein antibody
    • NIF antibody
    • p8 antibody
    • Pro-inflammatory S100 cytokine antibody
    • Protein S100-A8 antibody
    • S100 calcium binding protein A8 (calgranulin A) antibody
    • S100 calcium binding protein A8 antibody
    • S100 calcium-binding protein A8 antibody
    • S100A8 antibody
    • S100A8/S100A9 complex, included antibody
    • S10A8_HUMAN antibody
    • Urinary stone protein band A antibody
    see all

Anti-MRP8 antibody [CF-145] (Biotin) (ab114050) 使用論文

ab114050 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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