製品の概要

  • 製品名Anti-MPRIP antibody
    MPRIP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MPRIP
  • 特異性ab111381 detects endogenous levels of total MPRIP protein.
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human MPRIP.

  • ポジティブ・コントロール
    • Human lymph node tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
  • 配列類似性Contains 2 PH domains.
  • 細胞内局在Cytoplasm > cytoskeleton. Colocalizes with F-actin.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 9530046C02 antibody
    • AA536749 antibody
    • AI647711 antibody
    • C76423 antibody
    • KIAA0864 antibody
    • M-RIP antibody
    • MGC67316 antibody
    • mKIAA0864 antibody
    • Mprip antibody
    • MPRIP_HUMAN antibody
    • Myosin phosphatase Rho-interacting protein antibody
    • p116 Rho-interacting protein antibody
    • p116Rip antibody
    • Rho-interacting protein 3 antibody
    • Rhoip3 antibody
    • RIP3 antibody
    • RP23-180B18.4 antibody
    see all

Anti-MPRIP antibody 画像

  • ab111381 at 1/50 dilution staining MPRIP in paraffin-embedded Human Lymph tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-MPRIP antibody (ab111381) 使用論文

ab111381 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"