製品の概要

  • 製品名Anti-MPP5 antibody
    MPP5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MPP5
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human MPP5 conjugated to Keyhole Limpet Haemocyanin (KLH).

  • ポジティブ・コントロール
    • 293T cell lysate Human spleen tissue

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab113243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 77 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.
  • 組織特異性Expressed in the retina (at protein level).
  • 配列類似性Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 2 L27 domains.
    Contains 1 PDZ (DHR) domain.
    Contains 1 SH3 domain.
  • ドメインThe L27 domain 1 functions in targeting to the tight junctions by binding to INADL.
    The PDZ domain binds to the C-terminus of SC6A1.
  • 細胞内局在Cell membrane. Endomembrane system. Cell junction > tight junction. Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. In the retina, detected at the outer limiting membrane (OLM), apical to the adherens junction (AJ), where it colocalizes with CRB1. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM). Localized to the Purkinje cell body and axon.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ12615 antibody
    • MAGUK p55 subfamily member 5 antibody
    • Membrane protein palmitoylated 5 antibody
    • MPP 5 antibody
    • MPP5 antibody
    • MPP5_HUMAN antibody
    • PALS 1 antibody
    • PALS1 antibody
    • Protein associated with Lin-7 antibody
    • Stardust (Drosophila) antibody
    • Stardust antibody
    see all

Anti-MPP5 antibody 画像

  • Anti-MPP5 antibody (ab113243) at 1/500 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 77 kDa
  • ab113243, at 10µg/ml, staining Human MPP5 in Formalin/PFA-fixed paraffin-embedded spleen tissue by Immunohistochemistry.

Anti-MPP5 antibody (ab113243) 使用論文

ab113243 has not yet been referenced specifically in any publications.

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