配列 This sequence is highly conserved in rat paxillin and is also found in all three isoforms, alpha, beta and gamma. There is low homology between this sequence and the conserved sequence site in human paxillin (around Serine 85).
修飾 phospho S83 特性
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Paxillin (phospho S83) antibody (
Concentration information loading... 前処理および保存
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium Azide
Paired box protein Pax 1
機能 Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
配列類似性 Belongs to the paxillin family. Contains 4 LIM zinc-binding domains.
翻訳後修飾 Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
細胞内局在 Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
Information by UniProt
Mouse Paxillin (phospho S83) peptide (ab42724) 使用論文
has not yet been referenced specifically in any publications.
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