製品の概要

  • 製品名
    Mouse IL6 ELISA Set (without plates)
    IL6 キット 製品一覧
  • サンプルの種類
    Cell culture supernatant, Serum, Plasma
  • アッセイタイプ
    Sandwich (quantitative)
  • 検出感度
    < 10 pg/ml
  • 検出範囲
    15.6 pg/ml - 500 pg/ml
  • ステップ
    Multiple steps standard assay
  • 種交差性
    交差種: Mouse
  • 製品の概要

    Abcam’s IL-6 Murine in vitro ELISA Set is designed for the quantitative measurement of Murine IL-6 in cell culture supernatants, buffered solutions, serum, plasma and other body fluids.

     

    This ELISA Set is intended to measure murine IL-6 in cell-culture supernatants, as well as in serum samples. The enclosed procedures provide general guidelines for ELISA preparation. This procedure may need some optimization depending on the plastic, matrix, standard range.

     

    The murine IL-6 ELISA Set includes both the capture and the detection antibodies as well as Horse-Radish peroxidase conjugated Streptavidin (HRP-Strep) and TMB which are the reagents used in the colour development step.

     

    Recognizes both natural and recombinant Murine IL6

  • アプリケーション
    適用あり: Sandwich ELISAmore details
  • 試験プラットフォーム
    Reagents

製品の特性

  • 保存方法
    Store at +4°C. Please refer to protocols.
  • 内容 5 x 96 tests 10 x 96 tests 15 x 96 tests
    Detection biotinylated anti-murine IL-6 antibody 1 x 0.55ml 2 x 0.55ml 3 x 0.55ml
    Murine IL6 Capture antibody 1 x 0.1ml 2 x 0.1ml 3 x 0.1ml
    Murine IL6 standard 5 vials 10 vials 15 vials
    Chromogen TMB Substrate Solution 2 vials 4 vials 6 vials
    Streptavidin-HRP 1 vial 2 vials 3 vials
  • 研究分野
  • 機能
    Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
  • 関連疾患
    Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
    Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.
  • 配列類似性
    Belongs to the IL-6 superfamily.
  • 翻訳後修飾
    N- and O-glycosylated.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 別名
    • B-cell stimulatory factor 2
    • BSF-2
    • BSF2
    • CDF
    • CTL differentiation factor
    • Hepatocyte stimulating factor
    • HSF
    • Hybridoma growth factor
    • IFN-beta-2
    • IFNB2
    • IL-6
    • IL6
    • IL6_HUMAN
    • Interferon beta-2
    • Interleukin 6
    • Interleukin-6
    see all
  • 参照データベース

    アプリケーション

    Our Abpromise guarantee covers the use of ab47596 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Sandwich ELISA Use at an assay dependent concentration.

    画像

    • Murine IL6 ELISA Set (ab47596)
      Murine IL6 ELISA Set (ab47596)
      Mouse IL6 Standard curve ranging from 15.6 to 500 pg/mL

    参考文献

    ab47596 has not yet been referenced specifically in any publications.

    ab47596 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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