製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Mouse
    • 配列
      LNHTILAGVHSNDHSVV
    • 領域
      348 to 364

関連製品

特性

Our Abpromise guarantee covers the use of ab39781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-EDG2 antibody (ab16217)

    Neutralising

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • 5031439C20
    • AI326300
    • EDG 2
    • Endothelial differentiation gene 2
    • Endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 2
    • GPCR 26
    • Gpcr26
    • Gpcr91
    • GPR26
    • Kdt2
    • LPA 1
    • LPA receptor 1
    • LPA receptor EDG2
    • LPA-1
    • lpA1
    • Lpar1
    • LPAR1_HUMAN
    • Lysophosphatidic acid receptor 1
    • Lysophosphatidic acid receptor Edg-2
    • Lysophosphatidic acid receptor EDG2
    • MGC105279
    • MGC29102
    • Mrec1.3
    • rec.1.3
    • Ventricular zone gene 1
    • vzg-1
    • VZG1
    see all
  • 機能
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
  • 組織特異性
    Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在
    Cell surface. Cell membrane. Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
  • Information by UniProt

参考文献

ab39781 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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