製品の概要

  • 製品名Anti-Morphine antibody [BDI263]
    Morphine 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [BDI263] to Morphine
  • 特異性Reacts with Codeine. Reactivity was determined by ELISA with competition assays. Does not react with Nalorphine, Meperidine or Methadone.
  • アプリケーション適用あり: ELISAmore details
  • 免疫原

    Morphine-BTG.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.15M PBS, pH 7.6
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)Purified from acites.
  • ポリ/モノモノクローナル
  • クローン名BDI263
  • アイソタイプIgG1
  • 軽鎖の種類lambda
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab21143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
  • 別名
    • Morphine 6 antibody

Anti-Morphine antibody [BDI263] (ab21143) 使用論文

This product has been referenced in:
  • Jalah R  et al. Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers. Bioconjug Chem 26:1041-53 (2015). ELISA ; Mouse . Read more (PubMed: 25970207) »
  • Matyas GR  et al. Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine 32:1473-9 (2014). ELISA . Read more (PubMed: 24486371) »

See all 3 Publications for this product

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There are currently no Abreviews or Questions for ab21143.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"