製品の概要

  • 製品名Anti-Morphine antibody
    Morphine 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Morphine
  • 特異性This antibody has a Kd of 2 nM for morphine and related alkaloids (e.g., codeine, nalorphine, andnaltrexone).
  • アプリケーション適用あり: ELISAmore details
  • 免疫原

    Morphine conjugated at the C6 position to bovine serum albumin.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab1060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報Dilute in PBS or medium which is identical to that used in the assay system.
    This antibody may be used inimmunoassays for detection of alkaloid/narcotic drugs
  • ターゲット情報

    • 関連性Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
    • 別名
      • Morphine 6 antibody

    Anti-Morphine antibody (ab1060) 使用論文

    This product has been referenced in:
    • Torres OB  et al. A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse. Anal Bioanal Chem 408:1191-204 (2016). Read more (PubMed: 26677020) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"