Anti-Monocarboxylic acid transporter 1 抗体 (ab98868)

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製品の概要

  • 製品名
    Anti-Monocarboxylic acid transporter 1 antibody
    Monocarboxylic acid transporter 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Monocarboxylic acid transporter 1
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cat
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 215-264 (EKAGKSGVKK DLHDANTDLI GRHPKQEKRS VFQTINQFLD LTLFTHRGFL) of Human Monocarboxylic acid transporter 1 (NP_003042)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • ポジティブ･コントロール
    • HT1080 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P 1/100.

ターゲット情報

  • 機能
    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
  • 組織特異性
    Widely expressed in normal and in cancer cells.
  • 関連疾患
    Symptomatic deficiency in lactate transport
    Familial hyperinsulinemic hypoglycemia 7
  • 配列類似性
    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
    • 別名
      • FLJ36745 antibody
      • HHF7 antibody
      • MCT 1 antibody
      • MCT antibody
      • MGC44475 antibody
      • Monocarboxylate transporter 1 antibody
      • Monocarboxylate transporter antibody
      • Monocarboxylate transporter isoform 1 antibody
      • Monocarboxylic acid transporter 1 antibody
      • MOT1_HUMAN antibody
      • Slc16a1 antibody
      • SLC16A1 protein antibody
      • Solute carrier family 16 (monocarboxylic acid transporters) member 1 antibody
      • Solute carrier family 16 member 1 (monocarboxylic acid transporter 1) antibody
      • Solute carrier family 16 member 1 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Monocarboxylic acid transporter 1 antibody (ab98868)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Monocarboxylic acid transporter 1 antibody (ab98868)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human bronchial epithelial tissue labelling Monocarboxylic acid transporter 1 with ab98868 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the membrane and cytoplasm. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - Monocarboxylic acid transporter 1. Right - Merge.
    • Western blot - Anti-Monocarboxylic acid transporter 1 antibody (ab98868)
      Western blot - Anti-Monocarboxylic acid transporter 1 antibody (ab98868)
      Anti-Monocarboxylic acid transporter 1 antibody (ab98868) at 1 µg/ml + HT1080 cell lysate at 10 µg

      Predicted band size: 54 kDa



      Gel concentration: 12%

    参考文献

    ab98868 has not yet been referenced specifically in any publications.

    ab98868 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

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    2 reviews or Q&A

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    Dear xxxxx,
    many thanks for your quick response! That is all the information I needed.
    Best regards and have a pleasant day,

    That's my pleasure.

    If you have any further questions in the future please do not hesitate to contact us again.

    Until then, I wish you all the best with your research.

    Dear Sir or Madam,
    we got the anti MCT1 antibody ab98868, which was, according to the
    data sheet, raised against amino acids 215-264 of human MCT1. Could
    you please tell me where (intra- or extracellular) the epitope is
    supposed to ...

    Read More

    Thank you for contacting us.

    The anti-Monocarboxylic acid transporter 1 antibody (ab98868) has been raised againsta synthetic peptide taken from the region 215-264 of the humanMonocarboxylic acid transporter 1 (SwissProt reference P53985). Th...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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